منابع مشابه
D-dimer testing in pregnancy.
During pregnancy, elevated markers of coagulation and fibrinolytic system activation, such as D-Dimer, indicate increased thrombin activity and increased fibrinolysis following fibrin formation. Testing for D-Dimer during pregnancy could therefore be useful for the diagnosis and prediction of a venous thromboembolic event (VTE) or pregnancy-related complications, and for monitoring antithrombot...
متن کاملD - Dimer levels in pregnancy
32 We performed a retrospective review of medical charts regarding blood D-dimer levels 33 determined cross-sectionally by latex agglutination assay in 1952 samples from 1185 34 women to determine changes in D-dimer levels according to stage of pregnancy. Three 35 of 17 women in whom further investigations were performed were found to have 36 clinical venous thromboembolism (VTE). The median an...
متن کاملD-dimer testing in laboratory practice.
BACKGROUND D-dimer is a reliable and sensitive index of fibrin deposition and stabilization. As such, its presence in plasma should be indicative of thrombus formation. There are many conditions unrelated to thrombosis in which D-dimer concentrations are high, however, making its positive predictive value rather poor. CONTENT Notwithstanding these limitations, D-dimer can be regarded as a mos...
متن کاملQualitative point-of-care D-dimer testing compared with quantitative D-dimer testing in excluding pulmonary embolism in primary care.
BACKGROUND General practitioners can safely exclude pulmonary embolism (PE) by using the Wells PE rule combined with D-dimer testing. OBJECTIVE To compare the accuracy of a strategy using the Wells rule combined with either a qualitative point-of-care (POC) D-dimer test performed in primary care or a quantitative laboratory-based D-dimer test. METHODS We used data from a prospective cohort ...
متن کاملD-dimer testing in suspected venous thromboembolism: an update.
Fibrin is the main thrombus component. Its production being definitely lower in in-patients than in outpatients. is followed by activation of the fibrinolytic system, resulting in plasmin generation and subsequent fibrin lysis (Figure 1). Dissolution of crosslinked fibrin leads to formation of specific degradation products, includMethods for measuring DD in blood ing D-dimer (DD),1 which can be...
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ژورنال
عنوان ژورنال: Pathophysiology of Haemostasis and Thrombosis
سال: 2003
ISSN: 1424-8832,1424-8840
DOI: 10.1159/000083822